Protein Modification Reagents
Medchemexpress LLC Dbco-peg1-nhs ester | 2228857-34-7 | 95.0% | C28H27N3O7 | 25 MG
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker designed for the synthesis of PROTACs. This click chemistry reagent contains a DBCO group, enabling it to undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with molecules containing azide groups
Medchemexpress LLC Pomalidomide-PEG6-C2-COOH | 2225148-49-0 | 99.0% | C28H39N3O12 | 25 MG
Pomalidomide-PEG6-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a 6-unit PEG linker used in PROTAC technology. It has a molecular weight of 609.62 and appears as a viscous liquid, light yellow to yellow in color. This product is for research use only.
- E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Contains a 6-unit PEG linker
- Used in PROTAC technology
Medchemexpress LLC Dspe-peg-biotin, MW 2000 | 385437-57-0 | 99.9% | 25 MG
DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker
- Facilitates PROTAC synthesis
- Targets proteins for degradation
- Utilizes the ubiquitin-proteasome system
Sigma Aldrich Fine Chemicals Biosciences Collagenase B from Clostri
Collagenase B is prepared from Clostridium histolyticum cultures by filtration ammonium sulfate precipitation dialysis and lyophilization. Collagenase from Clostridium histolyticum is a collagenolytic enzyme. It interacts with collagen-like substances and is responsible for the degradation of collagen into small peptides. It is widely used for the disaggregation of many types of tissues (e.g. lung heart muscle bone adipose tissue liver kidney cartilage mammary gland placentae blood vessels brain tumors) and for the preparation of single-cell suspensions for the establishment of primary cell culture systems. Collagenase B is recommended when yield and viability are important.
eMolecules N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 2107272-96-6 | | 10mg
Broadpharm | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | 10mg | 298819349 | BP-23008 | 97.000 | 2107272-96-6 | | 870.450 | C44H63ClF3N3O9
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Medchemexpress LLC Tco-peg4-vc-pab-mmae | 2758671-45-1 | 99.3% | 1522.91 | C78H127N11O19 | 1 MG
TCO-PEG4-VC-PAB-MMAE is a drug-linker conjugate used in antibody-drug conjugate (ADC) research and click-chemistry applications; it couples a trans-cyclooctene (TCO) reactive handle to a PEG4-spaced valine-citrulline-para-aminobenzyl (Val-Cit-PAB) cleavable linker and the cytotoxic payload MMAE.
- High purity (99.3%).
- Molecular weight 1522.91 g/mol.
- Chemical formula C78H127N11O19.
- CAS number 2758671-45-1.
- Suitable for iEDDA click chemistry with tetrazine reagents.
- Intended for ADC synthesis and conjugation research.
- Store at -20°C and protect from light; in solvent store at -80°C up to 6 months or -20°C up to 1 month.
- Available in small research pack sizes (e.g., 1 MG).
Medchemexpress LLC Mal-PEG4-C2-NH2 (TFA) | 2512227-13-1 | 98.6% | 430.37 | 100 MG
Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These compounds utilize the ubiquitin-proteasome system to selectively degrade target proteins, making them valuable laboratory chemicals for substance manufacturing.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azido-PEG4-Amido-Tris | 1398044-55-7 | 96.4% | C15H30N4O8 | 50 MG
Azido-PEG4-Amido-Tris is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an azide group. It can engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing alkyne groups, and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with an azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
eMolecules Fmoc-NH-PEG10-CH2CH2COOH | 2101563-45-3 | MFCD28122954 | 1g
Ambeed | Fmoc-NH-PEG10-CH2CH2COOH | 1g | 524982680 | A100154 | | 2101563-45-3 | MFCD28122954 | 751.867 | C38H57NO14
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Medchemexpress LLC m-PEG12-Thiol | 2413368-61-1 | 95.0% | C25H52O12S | 100 MG
m-PEG12-Thiol is a PEG-based PROTAC linker, pivotal for synthesizing PROTACs. These bifunctional molecules are engineered to induce the degradation of specific target proteins within cells.
- Composed of two distinct ligands connected by a linker
- One ligand recruits an E3 ubiquitin ligase
- The other ligand binds to the target protein for degradation
- Utilizes the cell's ubiquitin-proteasome system
- Enables selective degradation of target proteins
BEZWADA BIOMEDICAL LLC PEG Diacrylate, MW 10,000, 5.0 GM
Acrylate/methacrylate end functionalization enables crosslinking. Polymers used in drug delivery and various biomedical applications
BEZWADA BIOMEDICAL LLC Poly (PEG-co-L-lactide-co-glycolde), PEG:L-lactide:glycolide, 5.0 GM
Copolymer of PEG with absorbable polymers such as PLGA, PLA or PCL.The polymer is completely hydrolysable aand have controllable hydrolytic degradation profile. Polymers used in drug delivery and various biomedical applications
![eMolecules Broadpharm / Fluorescein-PEG-Biotin MW 2000 / 10mg / 672542394 / BP-26046 / 90.000 / / [null] / 719.830 / C35H37N5O8S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502494401.JPG-250.jpg)
eMolecules Broadpharm / Fluorescein-PEG-Biotin MW 2000 / 10mg / 672542394 / BP-26046 / 90.000 / / [null] / 719.830 / C35H37N5O8S2
Broadpharm / Fluorescein-PEG-Biotin MW 2000 / 10mg / 672542394 / BP-26046 / 90.000 / / [null] / 719.830 / C35H37N5O8S2
